VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Tiger

Scientific Name: Panthera tigris altaica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Carnivora-> Feliformia-> Felidae-> Pantherinae-> Panthera-> Panthera tigris

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Human immunodeficiency virus 2

Family: Reoviridae

Receptor: CD4

Receptor CD4 information

Summary: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0023 2021.04 10X Genomics Heart Normal 16479 Link
Vthunter_0024 2021.04 10X Genomics Kidney Normal 3483 Link
Vthunter_0025 2021.04 10X Genomics Liver Normal 10237 Link
Vthunter_0026 2021.04 10X Genomics Lung Normal 14159 Link
Vthunter_0027 2021.04 10X Genomics Spleen Normal 33029 Link
Vthunter_0057 2021.04 iDrop PBMC Normal 4755 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of CD4 in human tissues   [NCBI]

Expression: Broad expression in spleen (RPKM 82.4), lymph node (RPKM 55.1) and 19 other tissues

Protein expression of CD4 in human tissues   [Proteinatlas]